{"product_id":"kpv","title":"KPV 10mg vial","description":"\u003ch1\u003eKPV\u003c\/h1\u003e\n\u003cp\u003eKPV is a naturally occurring tripeptide composed of the amino acids \u003cstrong\u003elysine, proline and valine\u003c\/strong\u003e. It is derived from \u003cstrong\u003ealpha-melanocyte-stimulating hormone (α-MSH)\u003c\/strong\u003e and has attracted significant scientific interest for its potential anti-inflammatory and immunomodulatory properties. Compared with the parent hormone, KPV is believed to offer greater stability while retaining many of its biological activities, making it an important area of ongoing research.\u003c\/p\u003e\n\u003ch2\u003eChemical Identifiers\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 67727-97-3\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₁₆H₃₀N₄O₄\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePubChem CID:\u003c\/strong\u003e 125672\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChEMBL:\u003c\/strong\u003e CHEMBL3235483\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemSpider:\u003c\/strong\u003e 111779\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrugBank:\u003c\/strong\u003e DB05479\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eAreas of Research Interest\u003c\/h2\u003e\n\u003cp\u003eCurrent preclinical and laboratory research is investigating KPV for its potential to:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eModulate inflammatory signalling pathways.\u003c\/li\u003e\n\u003cli\u003eSupport normal intestinal barrier function in experimental models.\u003c\/li\u003e\n\u003cli\u003ePromote tissue repair following inflammatory injury.\u003c\/li\u003e\n\u003cli\u003eReduce markers associated with oxidative stress.\u003c\/li\u003e\n\u003cli\u003eInfluence immune signalling without broadly suppressing normal immune function.\u003c\/li\u003e\n\u003cli\u003eDemonstrate antimicrobial activity against selected microorganisms in laboratory studies.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAlthough these findings are encouraging, further research is required to determine their relevance and safety in humans.\u003c\/p\u003e\n\u003ch2\u003eProposed Mechanisms Under Investigation\u003c\/h2\u003e\n\u003ch3\u003eNF-κB Modulation\u003c\/h3\u003e\n\u003cp\u003eResearch suggests KPV may influence the NF-κB signalling pathway, a key regulator of inflammatory responses. By modulating this pathway, KPV has been shown in experimental models to reduce the production of certain pro-inflammatory mediators.\u003c\/p\u003e\n\u003ch3\u003ePepT1 Cellular Transport\u003c\/h3\u003e\n\u003cp\u003eStudies indicate that KPV may enter cells via the PepT1 peptide transporter, particularly within the gastrointestinal tract. This transport mechanism is an active area of investigation for understanding peptide delivery during inflammatory processes.\u003c\/p\u003e\n\u003ch3\u003eMAPK Signalling\u003c\/h3\u003e\n\u003cp\u003eExperimental research has shown that KPV may influence MAPK signalling pathways, including ERK and p38 MAPK, both of which play important roles in cellular responses to inflammation and oxidative stress.\u003c\/p\u003e\n\u003ch3\u003eOxidative Stress\u003c\/h3\u003e\n\u003cp\u003eLaboratory studies suggest KPV may reduce the production of reactive oxygen species (ROS) and help protect cells from oxidative damage, although further investigation is required.\u003c\/p\u003e\n\u003ch2\u003eCurrent Research Applications\u003c\/h2\u003e\n\u003cp\u003eScientists are exploring KPV in a variety of experimental settings, including:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGastrointestinal inflammation and intestinal barrier research.\u003c\/li\u003e\n\u003cli\u003eSkin biology and inflammatory skin models.\u003c\/li\u003e\n\u003cli\u003eImmune regulation and inflammatory signalling.\u003c\/li\u003e\n\u003cli\u003eTissue repair and wound healing models.\u003c\/li\u003e\n\u003cli\u003eOxidative stress and cellular protection.\u003c\/li\u003e\n\u003cli\u003eMicrobiome and antimicrobial research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese remain areas of active scientific investigation and should not be interpreted as established therapeutic uses.\u003c\/p\u003e\n\u003ch2\u003eSummary\u003c\/h2\u003e\n\u003cp\u003eKPV continues to generate considerable interest within the scientific community because of its selective anti-inflammatory properties demonstrated in preclinical research. Its ability to influence multiple biological pathways without acting as a broad immunosuppressant makes it an important peptide for continued laboratory investigation. While early findings are promising, robust clinical studies are still needed to fully understand its safety, effectiveness and potential future applications.\u003c\/p\u003e\n\u003ch2\u003eResearch Disclaimer\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eFor Research Use Only. Not intended for human consumption, diagnosis, treatment, cure or prevention of any disease. Products supplied by Hybrid 2.0 are intended strictly for laboratory and scientific research purposes. Any information provided is for educational and scientific discussion only and should not be interpreted as medical advice or evidence of clinical efficacy.\u003c\/strong\u003e\u003c\/p\u003e","brand":"hybrid2.0","offers":[{"title":"Default Title","offer_id":58787813753157,"sku":null,"price":32.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1069\/2870\/1765\/files\/rn-image_picker_lib_temp_0ef26d3c-392c-4181-ad80-4499b0edcad0.png?v=1786033059","url":"https:\/\/hybrid2-0.co.uk\/products\/kpv","provider":"hybrid2.0","version":"1.0","type":"link"}